mic​roscopy

Digital Camera

The first digital camera sensor (CCD, charged-coupled device) was invented at Bell Labs in year 1969. Early uses of digital sensors werely mainly on military and scientific. It was until the 2000s that the fast-evolving CMOS sensor , with   its cost effectiveness,  began to overtake CCD and successfully popularized digital imaging to all aspects of our lives.

Microscopy industry benefitted from the revolutionary development  of digital camera sensor over the last two decades. Besides having higher live view speed and higher sensitivity, digital sensor is integrated into microscopy system to  provide auto focus and 3D surface functions these days. 

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CCD vs CMOS sensors

Optical microscope (OM) uses photon (light), has a resolution limit of 200 nm (max around 1000x-2000x), offers quick and easy observation even on living specimen with colour information.
Electron microscope (EM) manages to observe in mega magnification and sub-nano resolution. However, the process is slower and costlier due to the destructive preparation. Higher depth of field image can be achieved using its electron beam though only rendered in greyscale.

# Microscopes listed here are entirely optical microscopes.

High pixel count camera = High quality image?

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Sensitivity in microscopy digital camera

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